Synthesis of β-Amino-Functionalized α-exo-Methylene-γ-butyrolactones via a β-Lactam Synthon Strategy
نویسندگان
چکیده
منابع مشابه
Convenient synthesis of α,β-unsaturated γ-butyrolactones and γ-butyrolactams via decarboxylative iodination of paraconic acids and β-carboxyl-γ-butyrolactams using 1,3-diiodo-5,5-dimethylhydantoin.
A convenient synthetic approach to α,β-unsaturated γ-butyrolactones and α,β-unsaturated γ-butyrolactams is developed. The reaction proceeds via decarboxylative iodination of paraconic acids and β-carboxyl-γ-butyrolactams, employing 1,3-diiodo-5,5-dimethylhydantoin (DIH) under irradiation, followed by dehydroiodination of β-iodo-γ-butyrolactones and γ-butyrolactams providing good yields of α,β-u...
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ژورنال
عنوان ژورنال: Synthesis
سال: 2010
ISSN: 0039-7881,1437-210X
DOI: 10.1055/s-0030-1257870